Prototyping microfluidic devices for spatial multi-dimensional liquid chromatography by using Digital light processing 3D-printing


Spatial multi-dimensional liquid chromatography (MD-LC) is a promising separation technology that provides superior resolving power. The technique involves a three-dimensional separation space that allows for maximum peak capacity. Compared to conventional 2D-LC or 3D-LC systems, the analysis time is significantly reduced as fractions in the second and third dimensions are analyzed in parallel. This novel separation concept requires the construction of a device in which analytes are separated by their position in a three-dimensional separation space. Digital light processing (DLP) 3D printing is one of the best suited techniques for the fabrication of complex microfluidic devices with many interconnected microchannels, as encountered in spatial MD-LC.

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Ali Amini

Ali Amini

About the speaker

Ali Amini obtained his BSc and MSc in Mechanical Engineering and nano and microelectromechanical systems engineering (N/MEMS). He is currently a PhD student at the Vrije Universiteit Brussel in the chemical engineering department under the supervision of Prof. Dr. S. Eeltink. His scientific research is focused on multi-dimensional liquid chromatographic separations, specifically in the engineering of microdevices for spatial multi-dimensional liquid chromatography.

Lab Technology 2023