Safely synthesising with CO

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Beeld: Sarah Vangrunderbeeck

With a dual-chamber system, you can use carbon monoxide to install a carbonyl group during synthesis in a relatively safe way, a Flemish team shows in the European Journal of Organic Chemistry.

Usually chemists shy away from using carbon monoxide in organic synthesis because of the high toxicity and flammability of the gas. But if you can control those properties, you have a reactive carbonyl group in hand that offers numerous synthetic possibilities.

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